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Cat. No.: HY-P86025

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Oct-2 Antibody (YA5717)

Name: Oct-2 Antibody (YA5717)
Brand: MedChemExpress
SKU: HY-P86025
Availability: PreOrder

(Synonyms: POU domain, class 2, transcription factor 2; Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; Octamer-binding protein 2; Oct-2; Octamer-binding transcription factor 2; OTF-2; )

Oct-2 Antibody (YA5717) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Oct-2.

For research use only. We do not sell to patients.

Host:
Mouse
Isotype:
IgG2b
Application:
IHC-P, ELISA
Reactivity :
Human, Mouse,

Formulation:
Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Conjugation:
Non-conjugated

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications
Product Details
Product Properties
- Appearance
- Formulation
- Storage & Stability
- Shipping
Background
Documentation
Help & FAQs
Classifications
Bioz

Applications

Application	IHC-P IHC-P: Immunohistochemistry-Paraffin	ELISA ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio	1:200-400	1:500-5000

Product Details

Description

Oct-2 Antibody (YA5717) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Oct-2.

Host Mouse
Clonality Monoclonal
Species Reactivity
Human, Mouse,
Calculated Molecular Weight Predicted band size: 51 kDa;

Immunogen

Synthesized peptide derived from human Oct-2 AA range: 250-350

Purification

affinity chromatography.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG2b

Product Properties

Appearance

Liquid
Formulation

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Background

Function

2026-10-02 00:00:00 transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates IL6 expression in B cells with POU2AF1. Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR; Activates the U2 small nuclear RNA (snRNA) promoter^[1]^[2]^[3]^[4].
Subcellular Localization

Cytoplasm; Nucleus
Expression

Tissue_specificity:Isomer 3 is B cell specific. Isomer 5 is expressed in B cells and the immunoglobulin-expressing T cell line MOLT-4, but not in the T cell line BW5147.
Isoforms & Post-Translational Modification

P09086 has 5 isomers: P09086-1: 51209 Da (predicted); P09086-2: 49801 Da (predicted); P09086-3: 49461 Da (predicted); P09086-4: 43528 Da (predicted); P09086-5: 62172 Da (predicted).
Subunit

Interacts with NR3C1, AR and PGR (PubMed:10480874). Interacts with POU2AF1; the interaction increases POU2F2 transactivation activity (PubMed:7859290)
SwissProt ID

P09086
Gene ID

5452 [NCBI]
Synonyms

POU domain, class 2, transcription factor 2; Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; Octamer-binding protein 2; Oct-2; Octamer-binding transcription factor 2; OTF-2;