OSBPL11 Antibody (YA8233)

Cat. No.: HY-P88549: Data Sheet User Guide for Antibodies
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OSBPL11 Antibody (YA8233) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to OSBPL11.

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사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

OSBPL11 Antibody (YA8233) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to OSBPL11.

Host

Mouse

Clonality

Monoclonal

분자량

Predicted band size: 83.5 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9BXB4

Immunogen

Full length human recombinant protein of human OSBPL11 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Plays a role in regulating ADIPOQ and FABP4 levels in differentiating adipocytes and is also involved in regulation of adipocyte triglyceride storage (PubMed:23028956). Weakly binds 25-hydroxycholesterol (PubMed:17428193). Interacts with OSBPL9 to function as lipid transfer proteins (PubMed:39106189). Together they form a heterodimer that localizes at the ER-trans-Golgi membrane contact sites, and exchanges phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L-serine, PS) for phosphatidylinositol-4-phosphate (1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate), PI(4)P) between the two organelles, a step that is critical for sphingomyelin synthesis in the Golgi complex (PubMed:39106189)

Subcellular Localization：Late endosome membrane,Golgi apparatus, trans-Golgi network membrane

Expression：
Tissue_Specificity: Present at highest levels in ovary, testis, kidney, liver, stomach, brain, and adipose tissue. Strong expression (at protein level) in epithelial cells of kidney tubules, testicular tubules, caecum, and skin (PubMed:20599956). Present at low levels in subcutaneous and visceral adipose tissue (at protein level) (PubMed:23028956)

Isoforms & Post-Translational Modification：Q9BXB4: 747 amino acids, molecular weight 83643 Da.

Subunit：Heterodimer with OSBPL9

Synonyms

ORP-11; ORP11; OSBP12; TCCCIA00292

각종 서류

User Guide for Antibodies (1077 KB)