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PDXK Antibody (YA3496)(PBS only)

(Synonyms: PKH; PNK; HMSN6C; PRED79; C21orf97; HEL-S-1a; C21orf124)

PDXK Antibody (YA3496) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PDXK.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG

  • Application:

    WB, IHC-P, ICC/IF, FC

  • Reactivity :

    Human, Mouse

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • PDXK Antibody (YA3496)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
Dilution Ratio 1:500-1:2000 1:200-1:1000 1:50-1:200 1:200-1:400

Product Details

Description

PDXK Antibody (YA3496) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PDXK.

  • Host Mouse
  • Species Reactivity
    Human, Mouse
  • Observed Molecular Weight
    Observed band size: 35 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 35 kDa
Immunogen

Purified recombinant fragment of human PDXK (AA:1-312) expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Isotype

IgG

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    PDXK catalyzes the phosphorylation of the dietary vitamin B6 vitamers pyridoxal (PL), pyridoxine (PN) and pyridoxamine (PM) to form pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), respectively (Probable). PLP is the active form of vitamin B6, and acts as a cofactor for over 140 different enzymatic reactions[1][2][3][4][5].

  • Subcellular Localization

    Cytoplasm, cytosol

  • Expression


    Tissue_specificity:Ubiquitous (PubMed:31187503, PubMed:9099727) . Highly expressed in testis (PubMed:9099727) ; In adult testis and spermatozoa

    Induction:Transcriptionally regulated by Sp1 transcription factor

  • Isoforms & Post-Translational Modification

    O00764 has 3 isomers: O00764-1: 35102 Da (predicted); O00764-2: 31808 Da (predicted); O00764-3: 26827 Da (predicted).

  • Subunit

    Homodimer

  • SwissProt ID

    O00764

  • Gene ID
    8566 [NCBI]
  • Synonyms

    PKH; PNK; HMSN6C; PRED79; C21orf97; HEL-S-1a; C21orf124

PDXK Antibody (YA3496)(PBS only) Related Classifications

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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • PDXK Antibody (YA3496)(PBS only) Product Image