PLGF Antibody (YA1434)
(Synonyms: Pgf; PGFL; PIGF; Placenta growth factor; Placental growth factor; vascular endothelial growth factor related protein; PlGF; PlGF2; SHGC 10760)PLGF Antibody (YA1434) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PLGF.
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Host:
Rabbit
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Isotype:
IgG
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Application:
FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:50-1:100 | 1:10000 |
Product Details
PLGF Antibody (YA1434) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PLGF.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 24 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 25 kDa
Recombinant human PGF protein
Endogenous
Affinity Chromatography
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PLGF is a Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth
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Subcellular Localization
Secreted
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Expression
Tissue_specificity:Although all three isoforms are present in most placental tissues, PlGF-2 is specific to the early (8-week) placenta, while only PlGF-1 is found in colon and breast cancer. -
Isoforms & Post-Translational Modification
P49763 has 4 isomers: P49763-1: 24789 Da (predicted); P49763-2: 16725 Da (predicted); P49763-3: 19338 Da (predicted); P49763-4: 27402 Da (predicted).
N-glycosylated -
Subunit
Antiparallel homodimer; disulfide-linked. Also found as heterodimer with VEGFA/VEGF. Isoform PlGF-3 is found both as homodimer and as monomer
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SwissProt ID
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Synonyms
Pgf; PGFL; PIGF; Placenta growth factor; Placental growth factor; vascular endothelial growth factor related protein; PlGF; PlGF2; SHGC 10760
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Research Field
Cardiovascular
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