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  5. PLGF Antibody (YA1434)

PLGF Antibody (YA1434) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PLGF.

For research use only. We do not sell to patients.

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50 μL   Get quote  
100 μL   Get quote  

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

PLGF Antibody (YA1434) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PLGF.
Host

Rabbit
Clonality

Recombinant, Monoclonal
Molecular Weight
Predicted band size: 25 kDa;
Observed band size: 24 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Gene ID
Immunogen

Recombinant human PGF protein
Application &
Dilution Ratio
Application Dilution Ratio
FC
FC: Flow Cytometry
1:50-1:100
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
1:10000
Sensitivity Endogenous Purity Affinity Chromatography
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth
Subcellular Localization：Secreted
Expression：
Tissue_specificity:Although all three isoforms are present in most placental tissues, PlGF-2 is specific to the early (8-week) placenta, while only PlGF-1 is found in colon and breast cancer.
Isoforms & Post-Translational Modification：P49763 has 4 isomers: P49763-1: 24789 Da (predicted); P49763-2: 16725 Da (predicted); P49763-3: 19338 Da (predicted); P49763-4: 27402 Da (predicted).
N-glycosylated
Subunit：Antiparallel homodimer; disulfide-linked. Also found as heterodimer with VEGFA/VEGF. Isoform PlGF-3 is found both as homodimer and as monomer
Database

Entrez Gene: 5228 Human

SwissProt: P49763 Human

OMIM: 601121 Human

Research Field

Cardiovascular
Synonyms
Pgf; PGFL; PIGF; Placenta growth factor; Placental growth factor; vascular endothelial growth factor related protein; PlGF; PlGF2; SHGC 10760
Documentation
User Guide for Antibodies (1077 KB)

PLGF Antibody (YA1434) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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PLGF Antibody (YA1434)
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HY-P81689
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