Phospho-AMPK alpha 2 (Thr172) Antibody

Cat. No.: HY-P80791: FAQs
Data Sheet SDS COA User Guide for Antibodies

Phospho-AMPK alpha 2 (Thr172) Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 62 kDa, targeting to Phospho-AMPK alpha 2 (Thr172). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

For research use only. We do not sell to patients.

Size	Price	Stock	Quantity
Free Sample		Apply now
10 μL	$70	In-stock	Estimated Time of Arrival: December 31
50 μL	$185	In-stock	Estimated Time of Arrival: December 31
100 μL	$300	In-stock	Estimated Time of Arrival: December 31
250 μL		Get quote

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Biological Activity
Technical Parameters
Properties
Documentation

Description	Phospho-AMPK alpha 2 (Thr172) Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 62 kDa, targeting to Phospho-AMPK alpha 2 (Thr172). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.
Background	AMPK alpha 2: The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008]
Tag	Free
Gene ID	5563
Synonyms	PRKAA2; AMPK; AMPK2; 5'-AMP-activated protein kinase catalytic subunit alpha-2; AMPK subunit alpha-2; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase
Molecular Weight	Predicted band size: 62 kDa
Purity	affinity purified
Conjugation	Non-conjugated
Research Field	Neuroscience
Product Categories	Primary Antibody; Rabbit Polyclonal Antibody
Host	Rabbit
Reactivity	Human, Mouse, Rat
SwissProt ID	P54646
Dilution Ratio	WB: 1:500-1:1,000
Application	WB
Appearance	Liquid
Formulation	Supplied in phosphate buffered saline (pH 7.4), 150 mM NaCl and 50% glycerol. Preservative: 0.02% sodium azide
Storage & Stability	Stored at -20°C. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG
Immunogen	Synthetic phosphopeptide corresponding to residues surrounding Thr172 of Human AMPK alpha.The exact sequence is proprietary to MCE.
Documentation	Select Batch: Data Sheet (234 KB) SDS (251 KB) COA (205 KB) User Guide for Antibodies (1077 KB)

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Phospho-AMPK alpha 2 (Thr172) Antibody

Biological Activity

Technical Parameters

Properties

Documentation

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