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PIK3AP1 Antibody (YA8438)(PBS only)

(Synonyms: BCAP)

PIK3AP1 Antibody (YA8438) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PIK3AP1.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    IHC-P, ICC/IF, FC

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • PIK3AP1 Antibody (YA8438)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
Dilution Ratio 1:150-500 1:100-250 1:100

Product Details

Description

PIK3AP1 Antibody (YA8438) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PIK3AP1.

  • Host Mouse
  • Species Reactivity
    Human, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 90.2 kDa
Immunogen

Full length human recombinant protein of human PIK3AP1 produced in HEK293T cell.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    PIK3AP1 is a Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL

  • Subcellular Localization

    Cytoplasm,Cell membrane

  • Expression


    Tissue_Specificity: Expressed in natural killer (NK) cells

  • Isoforms & Post-Translational Modification

    Q6ZUJ8 has three isomers: Q6ZUJ8-1: 90398 Da (predicted); Q6ZUJ8-2: 70412 Da (predicted); Q6ZUJ8-3: 45484 Da (predicted).
    Constitutively phosphorylated

  • Subunit

    Homooligomer (By similarity)

  • SwissProt ID

    Q6ZUJ8

  • Synonyms

    BCAP

PIK3AP1 Antibody (YA8438)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • PIK3AP1 Antibody (YA8438)(PBS only) Product Image