PLDN (Pallidin) Antibody (YA8193)
(Synonyms: BLOS6; HPS9; PA; PALLID; PLDN)PLDN (Pallidin) Antibody (YA8193) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PLDN (Pallidin).
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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FC
FC: Flow Cytometry
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|---|---|---|
| Dilution Ratio | 1:150-500 | 1:100 |
Product Details
PLDN (Pallidin) Antibody (YA8193) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PLDN (Pallidin).
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 19.6 kDa
Full length human recombinant protein of human PLDN produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PLDN component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process
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Subcellular Localization
Cytoplasm,Membrane
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Expression
Tissue_Specificity: Widely expressed -
Isoforms & Post-Translational Modification
Q9UL45 has three isomers: Q9UL45-1: 19744 Da (predicted); Q9UL45-2: 8599 Da (predicted); Q9UL45-3.
Phosphorylated -
Subunit
Interacts with BLOC1S4 and DTNBP1/BLOC1S7 (By similarity)
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SwissProt ID
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Synonyms
BLOS6; HPS9; PA; PALLID; PLDN
Documentation
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