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Cat. No.: HY-P87621

PSMB10 Antibody (YA7305)

PSMB10 Antibody (YA7305) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PSMB10.

For research use only. We do not sell to patients.

Formulation:
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	WB WB: Western Blot	IHC-P IHC-P: Immunohistochemistry-Paraffin	FC FC: Flow Cytometry
Dilution Ratio	1:1000-2000	1:50-200	1:20-100

Description

PSMB10 Antibody (YA7305) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PSMB10.

Host Rabbit
Clonality Monoclonal,Recombinant
Species Reactivity
Human
Observed Molecular Weight

Observed band size: 27 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 29 kDa

Immunogen

A synthesized peptide derived from human PSMB10

Sensitivity

Endogenous

Purification

affinity purified by Protein A

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Appearance

Liquid
Formulation

Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

PSMB10 is a The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides
Subcellular Localization

Cytoplasm,Nucleus
Expression

Induction: Up-regulated by IFNG/IFN-gamma (at protein level). Up-regulated by IRF1. Up-regulated by TNF (at protein level). Up-regulated by tetrodotoxin (TTX) in glial cells. Up-regulated in Crohn's bowel disease (CD). Up-regulated by CD40L via the NFKB1 pathway in cancer cells
Isoforms & Post-Translational Modification

P40306: 273 amino acids, molecular weight 28936 Da.
Subunit

The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits
SwissProt ID

P40306