PSMC2 Antibody (YA7145)

Cat. No.: HY-P87458: Data Sheet User Guide for Antibodies
FAQs
Technical Support

PSMC2 Antibody (YA7145) is a Mouse-derived and non-conjugated IgG1, Kappa monoclonal antibody, targeting to PSMC2.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

* Please select Quantity before adding items.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

PSMC2 Antibody (YA7145) is a Mouse-derived and non-conjugated IgG1, Kappa monoclonal antibody, targeting to PSMC2.

Host

Mouse

Clonality

Monoclonal,Recombinant

Molecular Weight

Predicted band size: 49kDa;

Observed band size: 30kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

P35998

Immunogen

Recombinant human PSMC2.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-2000

Sensitivity	Endogenous	Purity	affinity purified by Protein G
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1, k

Appearance

Liquid

Formulation

Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides

Subcellular Localization：Cytoplasm

Expression：Induction: Expression is not cell cycle-dependent and occurs throughout the cell cycle

Isoforms & Post-Translational Modification：P35998 has two isomers: P35998-1: 48634 Da (predicted); P35998-2: 33274 Da (predicted).
Monoubiquitinated by RNF181丨Phosphorylated (PubMed:28539385)

Subunit：Component of the 19S proteasome regulatory particle complex

Documentation

User Guide for Antibodies (1077 KB)