PSMC2 Antibody
(別名: MSS1, PSMC2, 26S proteasome regulatory subunit 7, 26S proteasome AAA-ATPase subunit RPT1, Proteasome 26S subunit ATPase 2)PSMC2 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to PSMC2.
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Host:
Mouse
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF, FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|---|---|
| Dilution Ratio | 1:1000-5000 | 1:500-1000 | 1:100-200 | 1:500-1000 |
Product Details
PSMC2 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to PSMC2.
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Host Mouse
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat Predicted Reactivity: Monkey
Note: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.
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Observed Molecular WeightObserved band size: 30kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 49kDa
Recombinant human PSMC2.
Endogenous
affinity purified by Protein G
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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輸送条件
Shipping with blue ice.
Background
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Function
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides
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Subcellular Localization
Cytoplasm
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Expression
Induction: Expression is not cell cycle-dependent and occurs throughout the cell cycle
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Isoforms & Post-Translational Modification
P35998 has two isomers: P35998-1: 48634 Da (predicted); P35998-2: 33274 Da (predicted).
Monoubiquitinated by RNF181丨Phosphorylated (PubMed:28539385) -
Subunit
Component of the 19S proteasome regulatory particle complex
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SwissProt ID
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別名
MSS1, PSMC2, 26S proteasome regulatory subunit 7, 26S proteasome AAA-ATPase subunit RPT1, Proteasome 26S subunit ATPase 2
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