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RFXANK Antibody (YA8393)(PBS only)

(Synonyms: ANKRA1; BLS; F14150_1; RFX-B)

RFXANK Antibody (YA8393) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RFXANK.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    IHC-P, ICC/IF, FC

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • RFXANK Antibody (YA8393)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
Dilution Ratio 1:150-500 1:100-250 1:100

Product Details

Description

RFXANK Antibody (YA8393) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RFXANK.

  • Host Mouse
  • Species Reactivity
    Human, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 25.4 kDa
Immunogen

Full length human recombinant protein of human RFXANK produced in HEK293T cell.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    RFXANK activates transcription from class II MHC promoters. Activation requires the activity of the MHC class II transactivator/CIITA. May regulate other genes in the cell. RFX binds the X1 box of MHC-II promoters. May also potentiate the activation of RAF1|Isoform 2 is not involved in the positive regulation of MHC class II genes[1][2][3].

  • Subcellular Localization

    Cytoplasm,Nucleus

  • Expression


    Tissue_Specificity: Ubiquitous

  • Isoforms & Post-Translational Modification

    O14593 has three isomers: O14593-1: 28102 Da (predicted); O14593-2: 24243 Da (predicted); O14593-3: 25652 Da (predicted).
    Phosphorylated by RAF1

  • Subunit

    Forms homodimers (By similarity)

  • SwissProt ID

    O14593

  • Synonyms

    ANKRA1; BLS; F14150_1; RFX-B

RFXANK Antibody (YA8393)(PBS only) Related Classifications

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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • RFXANK Antibody (YA8393)(PBS only) Product Image