SDR9C7 Antibody (YA8504)
(Synonyms: RDHS; SDR-O; SDRO)SDR9C7 Antibody (YA8504) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to SDR9C7.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
ICC/IF, FC
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Reactivity :
Human, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|
| Dilution Ratio | 1:100-250 | 1:100 |
Product Details
SDR9C7 Antibody (YA8504) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to SDR9C7.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Rat
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Calculated Molecular Weight Predicted band size: 35.1 kDa
Full length human recombinant protein of human SDR9C7 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
SDR9C7 plays a crucial role in the formation of the epidermal permeability barrier. Catalyzes the NAD+-dependent dehydrogenation of the linoleate 9,10-trans-epoxy-11E-13-alcohol esterified in omega-O-acylceramides (such as in N-[omega-(9R,10R)-epoxy-(13R)-hydroxy-(11E)-octadecenoyloxy]-acylsphing-4E-enine) to the corresponding 13-ketone, the reactive moiety required for binding of epidermal ceramides to proteins. Displays weak conversion of all-trans-retinal to all-trans-retinol in the presence of NADH. Has apparently no steroid dehydrogenase activity[1][2].
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Subcellular Localization
Cytoplasm
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Expression
Tissue_Specificity: Expressed in the skin (PubMed:28173123). Expressed in granular and cornified layers of the epidermis (at protein level) (PubMed:28173123). Highly expressed in liver (PubMed:12234675) -
Isoforms & Post-Translational Modification
Q8NEX9: 313 amino acids, molecular weight 35263 Da.
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SwissProt ID
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Synonyms
RDHS; SDR-O; SDRO
Documentation
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