Septin 7 Antibody (YA1927)(PBS only)
(Synonyms: septin 7; CDC3; CDC10; SEPT7; SEPT7A; NBLA02942)Septin 7 Antibody (YA1927) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Septin 7.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:1000-1:5000 | 1:50-1:100 |
Product Details
Septin 7 Antibody (YA1927) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Septin 7.
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Host Rabbit
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 51 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 51 kDa
Recombinant protein of human SEPT7 aa286-435.
Affinity Purified
Non-conjugated
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Septin 7 is a Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation[1].
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Subcellular Localization
Cytoplasm; Chromosome, centromere, kinetochore; Cytoplasm, cytoskeleton, spindle; Cleavage furrow; Midbody; Cytoplasm, cytoskeleton, cilium axoneme; Cell projection, cilium, flagellum
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Expression
Tissue_specificity:Widely expressed -
Isoforms & Post-Translational Modification
Q16181 has 2 isomers: Q16181-1: 50680 Da (predicted); Q16181-2: 50581 Da (predicted).
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Subunit
Septins polymerize into heterooligomeric protein complexes that form filaments, and associate with cellular membranes, actin filaments and microtubules. GTPase activity is required for filament formation.
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SwissProt ID
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Synonyms
septin 7; CDC3; CDC10; SEPT7; SEPT7A; NBLA02942
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Research Field
Tags & Cell Markers
Documentation
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