Septin 7 Antibody (YA1927)(PBS only)

Cat. No.: HY-P82182A: Data Sheet User Guide for Antibodies
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Septin 7 Antibody (YA1927) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Septin 7.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

Septin 7 Antibody (YA1927) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Septin 7.

Host

Rabbit

Molecular Weight

Predicted band size: 51 kDa;

Observed band size: 51 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q16181

Gene ID

989 [NCBI]

Immunogen

Recombinant protein of human SEPT7 aa286-435.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-1:5000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:100

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (PubMed:25588830)

Subcellular Localization：Cytoplasm; Chromosome, centromere, kinetochore; Cytoplasm, cytoskeleton, spindle; Cleavage furrow; Midbody; Cytoplasm, cytoskeleton, cilium axoneme; Cell projection, cilium, flagellum

Expression：
Tissue_specificity:Widely expressed

Isoforms & Post-Translational Modification：Q16181 has 2 isomers: Q16181-1: 50680 Da (predicted); Q16181-2: 50581 Da (predicted).

Subunit：Septins polymerize into heterooligomeric protein complexes that form filaments, and associate with cellular membranes, actin filaments and microtubules. GTPase activity is required for filament formation.

Research Field

Tags & Cell Markers

Synonyms

septin 7; CDC3; CDC10; SEPT7; SEPT7A; NBLA02942

Documentation

User Guide for Antibodies (1077 KB)