SH2D2A Antibody (YA8315)(PBS only)

Cat. No.: HY-P88631A: Data Sheet User Guide for Antibodies
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SH2D2A Antibody (YA8315) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SH2D2A.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

SH2D2A Antibody (YA8315) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SH2D2A.

Host

Mouse

Molecular Weight

Predicted band size: 42.8 kDa

Species Reactivity

Human

SwissProt ID

Q9NP31

Immunogen

Full length human recombinant protein of human SH2D2A produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Purity	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Could be a T-cell-specific adapter protein involved in the control of T-cell activation. May play a role in the CD4-p56-LCK-dependent signal transduction pathway. Could also play an important role in normal and pathological angiogenesis. Could be an adapter protein that facilitates and regulates interaction of KDR with effector proteins important to endothelial cell survival and proliferation

Subcellular Localization：Cytoplasm

Expression：
Tissue_Specificity: Expression limited to tissues of the immune system and, in particular, activated T-cells. Expressed in peripheral blood leukocytes, thymus and spleen. Much lower expression or undetectable, in brain, placenta, skeletal muscle, prostate, testis, ovary, small intestine, and colon. Expressed at low levels in unstimulated T-cells, but not expressed in normal resting or activated B-cells. According to PubMed:10692392, expression is not restricted to activated T-cells, but strongly expressed in blood cell lineages, the endothelium and other cell and tissue types, such as heart, lung, and liver
Induction: Rapidly induced after activation of T-cells. However, the gene continues to be expressed in long-term cultures of activated T-cells

Isoforms & Post-Translational Modification：Q9NP31 has four isomers: Q9NP31-1: 42934 Da (predicted); Q9NP31-2: 44078 Da (predicted); Q9NP31-3: 39846 Da (predicted); Q9NP31-4: 40954 Da (predicted).
Phosphorylated on tyrosine residues

Subunit：Interacts with KDR

Synonyms

F2771; SCAP; TSAD; VRAP

Documentation

User Guide for Antibodies (1077 KB)