SHB Antibody (YA6934)
(Synonyms: bA3J10.2 antibody)SHB Antibody (YA6934) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SHB.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, FC
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Reactivity :
Human
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Formulation:
Supplied in PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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FC
FC: Flow Cytometry
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|---|---|---|
| Dilution Ratio | 1:1000 | 1:500-1:1000 |
Product Details
SHB Antibody (YA6934) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SHB.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 55 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size：55 kDa
Synthetic peptide within Human SHB aa 450-509.
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
SHB is an Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells
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Subcellular Localization
Cytoplasm,Cell membrane
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Expression
Tissue_Specificity: Widely expressed -
Isoforms & Post-Translational Modification
Q15464 has two isomers: Q15464-1: 55042 Da (predicted); Q15464-2: 30703 Da (predicted).
Phosphorylated upon PDGFRA, PDGFRB, TCR, IL2 receptor, FGFR1 or VEGFR2 activation -
Subunit
Interacts with PTPN11 (By similarity)
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SwissProt ID
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Synonyms
bA3J10.2 antibody
Documentation
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