SIGLEC5/CD170 Antibody (YA7111)(PBS only)
(Synonyms: CD170, CD33L2, OBBP2, SIGLEC5, Sialic acid-binding Ig-like lectin 5, Siglec-5, CD33 antigen-like 2, Obesity-binding protein 2, OB-BP2, OB-binding protein 2)
Based on 1 Customer Validation
SIGLEC5/CD170 Antibody (YA7111) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to SIGLEC5/CD170.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:200-1:400 | 1:10000 |
Product Details
SIGLEC5/CD170 Antibody (YA7111) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to SIGLEC5/CD170.
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Host Mouse
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 60.7kDa;
Purified recombinant fragment of human CD170 (AA: extra 17-230) expressed in E. Coli.
affinity purified.
Non-conjugated
IgG2a
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS, pH 7.4.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
SIGLEC5/CD170 is a Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface
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Subcellular Localization
Membrane
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Expression
Tissue_Specificity: Expressed by monocytic/myeloid lineage cells. Found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. Expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differentiation -
Isoforms & Post-Translational Modification
O15389: 551 amino acids, molecular weight 60715 Da.
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SwissProt ID
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Synonyms
CD170, CD33L2, OBBP2, SIGLEC5, Sialic acid-binding Ig-like lectin 5, Siglec-5, CD33 antigen-like 2, Obesity-binding protein 2, OB-BP2, OB-binding protein 2
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