SLC27A5 Antibody (YA4586)(PBS only)
(別名: BAL; ACSB; BACS; FATP5; ACSVL6; FACVL3; FATP-5; VLACSR; VLCSH2; VLCS-H2)SLC27A5 Antibody (YA4586) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SLC27A5.
-
Host:
Mouse
-
Isotype:
IgG1
-
Application:
IHC-P, ELISA
-
Reactivity :
Human, Mouse
-
Formulation:
Supplied in PBS, pH 7.4.
-
Conjugation:
Non-conjugated
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
|
|---|---|---|
| Dilution Ratio | 1:200-1:1000 | 1:10000 |
Product Details
SLC27A5 Antibody (YA4586) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SLC27A5.
-
Host Mouse
-
Species ReactivityHuman, Mouse
-
Observed Molecular WeightObserved band size: 75 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 75 kDa
Purified recombinant fragment of human SLC27A5 (AA: 508-570) expressed in E. Coli.
affinity purified.
Non-conjugated
IgG1
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in PBS, pH 7.4.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
輸送条件
Shipping with blue ice.
Background
-
Function
May mediate the import of long-chain fatty acids (LCFA) by facilitating their transport across cell membranes (PubMed:20448275, PubMed:20530735). Also catalyzes the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates (PubMed:10479480). Mainly functions as a bile acyl-CoA synthetase catalyzing the activation of bile acids via ATP-dependent formation of bile acid CoA thioesters which is necessary for their subsequent conjugation with glycine or taurine (PubMed:10749848, PubMed:11980911). Both primary bile acids (cholic acid and chenodeoxycholic acid) and secondary bile acids (deoxycholic acid and lithocholic acid) are the principal substrates (PubMed:10749848, PubMed:11980911). In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate ((25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate or THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol (PubMed:11980911). Plays an important role in hepatic fatty acid uptake and bile acid reconjugation and recycling but not in de novo synthesis of bile acids (By similarity)
-
Subcellular Localization
Endoplasmic reticulum membrane; Multi-pass membrane protein; Microsome; Cell membrane; Multi-pass membrane protein
-
Expression
Tissue_specificity:Predominantly expressed in liver -
Isoforms & Post-Translational Modification
Q9Y2P5 has 2 isomers: Q9Y2P5-1: 75385 Da (predicted); Q9Y2P5-2: 66846 Da (predicted).
-
SwissProt ID
-
別名
BAL; ACSB; BACS; FATP5; ACSVL6; FACVL3; FATP-5; VLACSR; VLCSH2; VLCS-H2
ドキュメント
Powered by Bioz
