SNX9 Antibody (YA1953)(PBS only)

Cat. No.: HY-P82208A: Data Sheet User Guide for Antibodies
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SNX9 Antibody (YA1953) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SNX9.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

SNX9 Antibody (YA1953) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SNX9.

Host

Rabbit

Molecular Weight

Predicted band size: 67 kDa;

Observed band size: 78 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse

SwissProt ID

Q9Y5X1

Gene ID

51429 [NCBI]

Immunogen

Recombinant protein of human SH3PX1

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100
IHC-F IHC-F: Immunohistochemistry-Frozen	1:50-1:100
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200
IP IP: Immunoprecipitation	1:20

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Promotes internalization of TNFR. Promotes degradation of EGFR after EGF signaling. Stimulates the GTPase activity of DNM1. Promotes DNM1 oligomerization. Promotes activation of the Arp2/3 complex by WASL, and thereby plays a role in the reorganization of the F-actin cytoskeleton. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Has lower affinity for membranes enriched in phosphatidylinositol 3-phosphate

Subcellular Localization：Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side; Cell membrane; Peripheral membrane protein; Cytoplasmic side; Cytoplasmic vesicle, clathrin-coated vesicle; Golgi apparatus, trans-Golgi network; Cell projection, ruffle; Cytoplasm

Expression：
Tissue_specificity:Widely expressed, with highest levels in heart and placenta, and lowest levels in thymus and peripheral blood leukocytes

Subunit：Homodimer, and homooligomer. Heterodimer with SNX18. Interacts with ITCH. Interacts (via SH3 domain) with TNK2, WASL and ACTR3.

Research Field

Signal Transduction

Synonyms

SDP1; WISP; SH3PX1; SH3PXD3A

Documentation

User Guide for Antibodies (1077 KB)