SOD2 Antibody (YA670)

Cat. No.: HY-P80898: Data Sheet COA
SDS
User Guide for Antibodies
FAQs
Technical Support

SOD2 Antibody (YA670) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to SOD2.

For research use only. We do not sell to patients.

Size	Stock	Quantity
Free Sample	Apply now
10 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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SOD2 Antibody (YA670) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
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Background
Documentation

Description

SOD2 Antibody (YA670) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to SOD2.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 25 kDa;

Observed band size: 22 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

P04179

Gene ID

6648 [NCBI]

Immunogen

Synthetic peptide corresponding to Human SOD2.The exact sequence is proprietary to MCE.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000

Sensitivity	Endogenous	Purity	affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2b

Appearance

Liquid

Formulation

Supplied in 1*PBS (pH 7.3), 50% glycerol and 0.5% BSA. Preservative: 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Verification Image

Western blot analysis of extracts from K562 (lane 2(20μg) and K562 (lane 3(40μg) using SOD2 (HY-P80898) Mouse mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

Background

Function：Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems

Subcellular Localization：Mitochondrion matrix

Expression：
Induction:Expression is regulated by KRIT1

Isoforms & Post-Translational Modification：P04179 has 4 isomers: P04179-1: 24750 Da (predicted); P04179-2: 20724 Da (predicted); P04179-3: 18262 Da (predicted); P04179-4: 19730 Da (predicted).
Nitrated under oxidative stress. Nitration coupled with oxidation inhibits the catalytic activity;Acetylation at Lys-122 decreases enzymatic activity. Deacetylated by SIRT3 upon exposure to ionizing radiations or after long fasting (By similarity);Polyubiquitinated; leading to proteasomal degradation. Deubiquitinated by USP36 which increases protein stability

Subunit：Homotetramer

RRID

AB_3102742

Database

Entrez Gene: 6648 Human

SwissProt: P04179 Human

OMIM: 612634 Human

Research Field

Cell Biology

Synonyms

IPOB; IPO-B; MNSOD; MVCD6; Mn-SOD; SOD2

Documentation

Select Batch:

Data Sheet (232 KB) SDS (252 KB)

COA (205 KB)

User Guide for Antibodies (1077 KB)

SOD2 Antibody (YA670) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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SOD2 Antibody (YA670)

SOD2 Antibody (YA670) Featured Recommendations:

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Background

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SOD2 Antibody (YA670) Related Classifications

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