SOD2 Antibody (YA3635)

Cat. No.: HY-P83938: Data Sheet User Guide for Antibodies
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SOD2 Antibody (YA3635) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SOD2.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL	Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

SOD2 Antibody (YA3635) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SOD2.

Host

Mouse

Clonality

Monoclonal Antibody

Molecular Weight

Predicted band size: 25 kDa;

Observed band size: 22 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

P04179

Gene ID

6648 [NCBI]

Immunogen

Purified recombinant fragment of human SOD2 (AA: 1-222) expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-1:1000
FC FC: Flow Cytometry	1:200-1:400
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS with 0.05% sodium azide

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems

Subcellular Localization：Mitochondrion matrix

Expression：
Induction:Expression is regulated by KRIT1

Isoforms & Post-Translational Modification：P04179 has 4 isomers: P04179-1: 24750 Da (predicted); P04179-2: 20724 Da (predicted); P04179-3: 18262 Da (predicted); P04179-4: 19730 Da (predicted).
Nitrated under oxidative stress. Nitration coupled with oxidation inhibits the catalytic activity;Acetylation at Lys-122 decreases enzymatic activity. Deacetylated by SIRT3 upon exposure to ionizing radiations or after long fasting (By similarity);Polyubiquitinated; leading to proteasomal degradation. Deubiquitinated by USP36 which increases protein stability

Subunit：Homotetramer

Synonyms

IPOB; IPO-B; MNSOD; MVCD6; Mn-SOD

Documentation

User Guide for Antibodies (1077 KB)