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SULT1C2 Antibody (YA8162)(PBS only)

(Synonyms: humSULTC2; ST1C1; ST1C2; SULT1C1)

SULT1C2 Antibody (YA8162) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to SULT1C2.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2b

  • Application:

    IHC-P, FC

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • SULT1C2 Antibody (YA8162)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
FC Info
FC: Flow Cytometry
Dilution Ratio 1:150-500 1:100

Product Details

Description

SULT1C2 Antibody (YA8162) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to SULT1C2.

  • Host Mouse
  • Species Reactivity
    Human
  • Calculated Molecular Weight Predicted band size: 34.7 kDa
Immunogen

Full length human recombinant protein of human SULT1C2 produced in HEK293T cell.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG2b

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    SULT1C2 is a Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the sulfate conjugation of phenolic compounds. Does not transfer sulfate to steroids, dopamine, acetaminophen, or alpha-naphthol. Except in mitochondria, where it can add sulfate to cholesterol producing cholesterol sulfate, which alters mitochondrial membrane organization, and impacts protein complex mobility increasing state-III respiration, thereby modulating mitochondrial respiration. Catalyzes the sulfation of the carcinogenic N-hydroxy-2-acetylaminofluorene leading to highly reactive intermediates capable of forming DNA adducts, potentially resulting in mutagenesis[1][2][3].

  • Subcellular Localization

    Cytoplasm,Lysosome,Mitochondrion

  • Expression


    Tissue_Specificity: Found in adult stomach, kidney and thyroid gland, and in fetal kidney and liver

  • Isoforms & Post-Translational Modification

    O00338 has two isomers: O00338-1: 34880 Da (predicted); O00338-2: 35868 Da (predicted).

  • SwissProt ID

    O00338

  • Synonyms

    humSULTC2; ST1C1; ST1C2; SULT1C1

SULT1C2 Antibody (YA8162)(PBS only) Related Classifications

MOQ
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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • SULT1C2 Antibody (YA8162)(PBS only) Product Image
    1/16
  • SULT1C2 Antibody (YA8162)(PBS only) Product Image