Syndecan 1 Antibody (YA2526)
(Synonyms: SDC1; SDC; Syndecan-1; SYND1; CD138)
Based on 1 Customer Validation
Syndecan 1 Antibody (YA2526) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Syndecan 1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in rabbit IgG in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|
| Dilution Ratio | 1:1000-1:2000 | 1:100-1:200 | 1:50-1:200 |
Product Details
Syndecan 1 Antibody (YA2526) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Syndecan 1.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 35 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 32 kDa
Entrez Gene: 6382 Human ; 20969 Mouse ; 25216 Rat
SwissProt: P18827 Human ; P18828 Mouse ; P26260 Rat
OMIM: 186355 Human
A synthesized peptide derived from human Syndecan 1 aa1-254.
Endogenous
Affinity Chromatography
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in rabbit IgG in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Syndecan 1 cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway[1].
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Subcellular Localization
Membrane; Single-pass type I membrane protein; Secreted; Secreted, extracellular exosome
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Expression
Tissue_specificity:Protein levels were detected in the placenta (PubMed: 32337544) . Protein levels were detected in fibroblasts (PubMed: 36213313) . -
Subunit
Interacts with CDCP1. Interacts (via C-terminus) with TIAM1 (via PDZ domain). Interacts with MDK (By similarity)
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SwissProt ID
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Synonyms
SDC1; SDC; Syndecan-1; SYND1; CD138
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Research Field
Cell Biology
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