Synaptophysin Antibody (YA3702)
(Synonyms: MRXSYP; SYP)Synaptophysin Antibody (YA3702) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Synaptophysin.
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Host:
Mouse
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Isotype:
IgG1
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Application:
WB, IHC-P, ELISA
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Reactivity :
Human, Rat
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Formulation:
Supplied in PBS with 0.05% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:200-1:1000 | 1:10000 |
Product Details
Synaptophysin Antibody (YA3702) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Synaptophysin.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Rat
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Observed Molecular WeightObserved band size: 34 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 34 kDa
Purified recombinant fragment of SYP aa 224-313.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Synaptophysin is a Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity
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Subcellular Localization
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein; Synapse, synaptosome
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Expression
Tissue_specificity:This gene is expressed in the brain, primarily in the hippocampus, dentate gyrus neural stack (expression is higher in the outer half of the molecular layer than in the inner half) , and CA4 and CA3 neural stacks (PubMed: 8838578) . It is also expressed in the putamen (protein level) (PubMed: 17296554) . -
Isoforms & Post-Translational Modification
P08247 has 2 isomers: P08247-1: 33845 Da (predicted); P08247-2: 20757 Da (predicted).
Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation;Phosphorylated by SRC -
Subunit
Homohexamer or homotetramer. Interacts with SRCIN1 (PubMed:18662323). Interacts with VAMP2; the interaction is inhibited by interaction of VAPM2 with SEPT8 (By similarity)
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SwissProt ID
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Synonyms
MRXSYP; SYP
Documentation
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