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SYPL1 Antibody (YA7363)

(Synonyms: SYPL, SYPL1, Synaptophysin-like protein 1, Pantophysin)

SYPL1 Antibody (YA7363) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to SYPL1.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, IHC-P, FC

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS (pH7.4) containing 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • Conjugation:
    Non-conjugated
  • SYPL1 Antibody (YA7363) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
WB Info
WB: Western Blot
FC Info
FC: Flow Cytometry
Dilution Ratio 1:200-1:1000 1:1000-1:5000 1:100-1:500

Product Details

Description

SYPL1 Antibody (YA7363) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to SYPL1.

  • Host Rabbit
  • Clonality Monoclonal,Recombinant
  • Species Reactivity
    Human, Mouse, Rat
  • Observed Molecular Weight
    Observed band size: 28 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 28 kDa
Immunogen

The exact sequence is proprietary to MCE.

Sensitivity

Endogenous

Purification

Protein A affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in PBS (pH7.4) containing 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    Synaptophysin-like 1 (SYPL1), which belongs to the synaptophysin (SYP) family, was originally regarded as a neuroendocrine-related protein and is expressed in both neuronal and non-neuronal tissues. SYPL1 is reported as a component of transport vesicles, which associate with insulin-responsive glucose transporter type 4 (GLUT4)-containing vesicles in adipocytes and podocyte exosome-enriched fraction in urine. In a bioinformatics-based study, SYPL1 was predicted to play a vital role in papillary thyroid carcinoma[1].

  • Subcellular Localization

    Cytoplasmic vesicle membrane; Multi-pass membrane protein; Melanosome

  • Isoforms & Post-Translational Modification

    Synaptophysin Like Protein 1 has 2 isomers: Q16563-1: 28565 Da (predicted); Q16563-2: 26412 Da (predicted).

  • SwissProt ID

    Q16563

  • Synonyms

    SYPL, SYPL1, Synaptophysin-like protein 1, Pantophysin

References

[1]. Song Y, et al. SYPL1 Inhibits Apoptosis in Pancreatic Ductal Adenocarcinoma via Suppression of ROS-Induced ERK Activation. Front Oncol. 2020 Sep 15;10:1482.

SYPL1 Antibody (YA7363) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • SYPL1 Antibody (YA7363) Product Image