Thymidine Kinase Antibody (YA7683)
Thymidine Kinase Antibody (YA7683) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Thymidine Kinase.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, FC, ICC/IF, IP
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Reactivity :
Human
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Formulation:
Supplied in 10mM TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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FC
FC: Flow Cytometry
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IP
IP: Immunoprecipitation
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|---|---|---|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:50-100 | 1:50-100 | 1:50-100 | 1:20-50 |
Product Details
Thymidine Kinase Antibody (YA7683) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Thymidine Kinase.
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Host Rabbit
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Clonality Recombinant
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 25 kDa;
A synthesized peptide derived from human Thymidine kinase
Endogenous
affinity purified by Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 10mM TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Thymidine Kinase is a Cell-cycle-regulated enzyme of importance in nucleotide metabolism. Catalyzes the first enzymatic step in the salvage pathway converting thymidine into thymidine monophosphate. Transcriptional regulation limits expression to the S phase of the cell cycle and transient expression coincides with the oscillation in the intracellular dTTP concentration (Probable). Also important for the activation of anticancer and antiviral nucleoside analog prodrugs such as 1-b-d-arabinofuranosylcytosine (AraC) and 3c-azido-3c-deoxythymidine (AZT)[1][2].
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Subcellular Localization
Cytoplasm
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Isoforms & Post-Translational Modification
P04183: 234 amino acids, molecular weight 25469 Da.
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Subunit
Homotetramer (PubMed:14697231, PubMed:15611477, PubMed:15733844, PubMed:17407781, PubMed:22385435)
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SwissProt ID
Documentation
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