Thymidine Kinase Antibody (YA7683)

Cat. No.: HY-P87998: Data Sheet User Guide for Antibodies
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Thymidine Kinase Antibody (YA7683) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Thymidine Kinase.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

Thymidine Kinase Antibody (YA7683) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Thymidine Kinase.

Host

Rabbit

Clonality

Recombinant

Molecular Weight

Predicted band size: 25 kDa;

Species Reactivity

Human

SwissProt ID

P04183

Immunogen

A synthesized peptide derived from human Thymidine kinase

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-100
FC FC: Flow Cytometry	1:50-100
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-100
IP IP: Immunoprecipitation	1:20-50

Sensitivity	Endogenous	Purity	affinity purified by Protein A
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 10mM TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Cell-cycle-regulated enzyme of importance in nucleotide metabolism (PubMed:9575153). Catalyzes the first enzymatic step in the salvage pathway converting thymidine into thymidine monophosphate (PubMed:22385435). Transcriptional regulation limits expression to the S phase of the cell cycle and transient expression coincides with the oscillation in the intracellular dTTP concentration (Probable). Also important for the activation of anticancer and antiviral nucleoside analog prodrugs such as 1-b-d-arabinofuranosylcytosine (AraC) and 3c-azido-3c-deoxythymidine (AZT) (PubMed:22385435)

Subcellular Localization：Cytoplasm

Isoforms & Post-Translational Modification：P04183: 234 amino acids, molecular weight 25469 Da.

Subunit：Homotetramer (PubMed:14697231, PubMed:15611477, PubMed:15733844, PubMed:17407781, PubMed:22385435)

Documentation

User Guide for Antibodies (1077 KB)