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  4. Monoclonal Antibodies Flow Cytometry Antibodies
  5. TIPRL Antibody (YA7848)(PBS only)

TIPRL Antibody (YA7848)(PBS only)

Cat. No.: HY-P88164A
User Guide for Antibodies Technical Support

TIPRL Antibody (YA7848) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TIPRL.

For research use only. We do not sell to patients.

Size Stock
50 μL   Get quote  
100 μL   Get quote  

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

  • References

Description

TIPRL Antibody (YA7848) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TIPRL.
Host

Mouse
Molecular Weight

Predicted band size: 31.4 kDa
Species Reactivity
Human, Mouse, Rat
SwissProt ID
Immunogen

Full length human recombinant protein of human TIPRL produced in HEK293T cell.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-2000
FC
FC: Flow Cytometry
1:100
Purity Affinity purified Conjugation Non-conjugated
Isotype IgG1  
Appearance

Liquid
Formulation

Supplied in PBS, pH 7.4.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：May be a allosteric regulator of serine/threonine-protein phosphatase 2A (PP2A). Isoform 1 inhibits catalytic activity of the PP2A(D) core complex in vitro. The PP2A(C):TIPRL complex does not show phosphatase activity. Acts as a negative regulator of serine/threonine-protein phosphatase 4 probably by inhibiting the formation of the active PPP4C:PPP4R2 complex; the function is proposed to implicate it in DNA damage response by promoting H2AX phosphorylated on Ser-140 (gamma-H2AX). May play a role in the regulation of ATM/ATR signaling pathway controlling DNA replication and repair
Subcellular Localization：Cytoplasm
Isoforms & Post-Translational Modification：O75663 has two isomers: O75663-1: 31444 Da (predicted); O75663-2: 20214 Da (predicted).
Subunit：Isoform 1 interacts with PPP2CA
Synonyms
TIP; TIP41
Documentation
User Guide for Antibodies (1077 KB)
References

TIPRL Antibody (YA7848)(PBS only) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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