TMED1 Antibody (YA8573)
(Synonyms: Il1rl1l; IL1RL1LG; p24g1; Tp24)TMED1 Antibody (YA8573) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TMED1.
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Host:
Mouse
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Isotype:
IgG1
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Application:
FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
FC
FC: Flow Cytometry
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|---|---|
| Dilution Ratio | 1:100 |
Product Details
TMED1 Antibody (YA8573) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TMED1.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 22.8 kDa
Full length human recombinant protein of human TMED1 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
TMED1 is a Potential role in vesicular protein trafficking, mainly in the early secretory pathway. May act as a cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and may be involved in vesicle coat formation at the cytoplasmic side. Plays a positive role in IL-33-mediated IL-8 and IL-6 production by interacting with interleukin-33 receptor IL1RL1. Also plays a role in the modulation of innate immune signaling through the cGAS-STING pathway by interacting with RNF26[1][2].
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Subcellular Localization
Cell membrane,Endoplasmic reticulum membrane,Golgi apparatus, cis-Golgi network membrane,Endoplasmic reticulum-Golgi intermediate compartment membrane
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Expression
Tissue_Specificity: Widely expressed -
Isoforms & Post-Translational Modification
Q13445: 227 amino acids, molecular weight 25206 Da.
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Subunit
Homodimer in endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment and cis-Golgi network
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SwissProt ID
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Synonyms
Il1rl1l; IL1RL1LG; p24g1; Tp24
Documentation
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