TMOD1 (Tropomodulin 1) Antibody (YA8323)

Cat. No.: HY-P88639: Data Sheet User Guide for Antibodies
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TMOD1 (Tropomodulin 1) Antibody (YA8323) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to TMOD1 (Tropomodulin 1).

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

TMOD1 (Tropomodulin 1) Antibody (YA8323) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to TMOD1 (Tropomodulin 1).

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 40.4 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P28289

Immunogen

Full length human recombinant protein of human TMOD1 produced in HEk293 cell.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-250
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2b

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Blocks the elongation and depolymerization of the actin filaments at the pointed end (PubMed:38168645). The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus

Subcellular Localization：Cytoplasm, cytoskeleton

Expression：
Tissue_Specificity: Highly expressed in the erythrocyte, heart and skeletal muscle

Isoforms & Post-Translational Modification：P28289 has two isomers: P28289-1: 40569 Da (predicted); P28289-2: 26014 Da (predicted).

Subunit：Binds to the N-terminus of tropomyosin and to actin

Synonyms

D9S57E; ETMOD; TMOD

Documentation

User Guide for Antibodies (1077 KB)