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TMOD1 (Tropomodulin 1) Antibody (YA8323)

(Synonyms: D9S57E; ETMOD; TMOD)

TMOD1 (Tropomodulin 1) Antibody (YA8323) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to TMOD1 (Tropomodulin 1).

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG

  • Application:

    IHC-P, ICC/IF, FC

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

  • Conjugation:
    Non-conjugated
  • TMOD1 (Tropomodulin 1) Antibody (YA8323) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
Dilution Ratio 1:50-250 1:100-250 1:100

Product Details

Description

TMOD1 (Tropomodulin 1) Antibody (YA8323) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to TMOD1 (Tropomodulin 1).

  • Host Mouse
  • Clonality Monoclonal
  • Species Reactivity
    Human, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 40.4 kDa
Immunogen

Full length human recombinant protein of human TMOD1 produced in HEk293 cell.

Sensitivity

Endogenous

Purification

Affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Solution

  • Formulation

    Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    TMOD1 is a Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus[1].

  • Subcellular Localization

    Cytoplasm, cytoskeleton

  • Expression


    Tissue_Specificity: Highly expressed in the erythrocyte, heart and skeletal muscle

  • Isoforms & Post-Translational Modification

    P28289 has two isomers: P28289-1: 40569 Da (predicted); P28289-2: 26014 Da (predicted).

  • Subunit

    Binds to the N-terminus of tropomyosin and to actin

  • SwissProt ID

    P28289

  • Synonyms

    D9S57E; ETMOD; TMOD

TMOD1 (Tropomodulin 1) Antibody (YA8323) Related Classifications

MOQ
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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • TMOD1 (Tropomodulin 1) Antibody (YA8323) Product Image