DcR2 Antibody (YA4553)

Cat. No.: HY-P84856: Ficha de datos User Guide for Antibodies
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DcR2 Antibody (YA4553) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DcR2.

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Tamaño	Stock	Cantidad
20 μL	Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL	Obtener un presupuesto

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Descripciòn
Referencias

Descripciòn

DcR2 Antibody (YA4553) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DcR2.

Host

Mouse

Clonality

Monoclonal Antibody

Peso molecular

Predicted band size: 42 kDa;

Observed band size: 36 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse

SwissProt ID

Q9UBN6

Gene ID

8793 [NCBI]

Immunogen

Purified recombinant fragment of human TNFRSF10D (AA: extra 56-211) expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:2000
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Pureza	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS with 0.05% sodium azide

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background

Function：Receptor for the cytotoxic ligand TRAIL (PubMed:9430226). Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis (PubMed:9537512). Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway (PubMed:9382840, PubMed:9430226)

Subcellular Localization：Membrane; Single-pass type I membrane protein

Expression：
Tissue_specificity:This gene is widely expressed, especially in the fetal kidneys, lungs, and liver, as well as in the human testes and liver. It is also expressed in peripheral blood leukocytes, the colon and small intestine, ovaries, prostate, thymus, spleen, pancreas, kidneys, lungs, placenta, and heart.

Synonyms

DCR2; CD264; TRUNDD; TRAILR4; TRAIL-R4

Documentación

User Guide for Antibodies (1077 KB)

Referencias

[1]. /biology-dictionary/hct-116-cell.html [Content Brief]