WDR5 Antibody (YA4123)
(Synonyms: SWD3; BIG-3; WDR5)WDR5 Antibody (YA4123) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to WDR5.
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Host:
Mouse
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Isotype:
IgG
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Application:
WB, ELISA
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Reactivity :
Human
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Formulation:
Supplied in ascitic fluid containing 0.03% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:10000 |
Product Details
WDR5 Antibody (YA4123) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to WDR5.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 37 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 37 kDa
Purified recombinant fragment of human WDR5 aa 158-334.
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in ascitic fluid containing 0.03% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
WDR5 is a highly conserved WD40 repeat-containing protein that is essential for proper regulation of multiple cellular processes. WDR5 is best characterized as a core scaffolding component of histone methyltransferase complexes. WDR5 also plays a crucial role in mediating protein-protein interactions that sustain oncogenesis in human cancers. One prominent example is the interaction between the transcription factor MYC and WDR5, which is essential for oncogenic processes.
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Subcellular Localization
Nucleus
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Subunit
Interacts with HCFC1 (PubMed:12670868). Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (PubMed:19103755).
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SwissProt ID
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Synonyms
SWD3; BIG-3; WDR5
Documentation
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