WNT8A Antibody (YA6941)
(Synonyms: Protein Wnt-8a antibody; WNT 8A antibody; Wnt 8d antibody)WNT8A Antibody (YA6941) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to WNT8A.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF, FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|---|
| Dilution Ratio | 1:1000 | 1:50 | 1:500-1:1000 |
Product Details
WNT8A Antibody (YA6941) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to WNT8A.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 55 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size：38.8 kDa
Recombinant protein within human WNT8A aa 100-300 / 351.
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
WNT8A is a Ligand for members of the frizzled family of seven transmembrane receptors. Plays a role in embryonic patterning
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Subcellular Localization
Secreted, extracellular space, extracellular matrix,Secreted
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Isoforms & Post-Translational Modification
Q9H1J5 has three isomers: Q9H1J5-1: 38849 Da (predicted); Q9H1J5-2: 39527 Da (predicted); Q9H1J5-3: 40892 Da (predicted).
Palmitoleoylation is required for efficient binding to frizzled receptors (By similarity)丨Proteolytic processing by TIKI1 and TIKI2 promotes oxidation and formation of large disulfide-bond oligomers, leading to inactivation of WNT8A -
Subunit
Forms a soluble 1:1 complex with AFM; this prevents oligomerization and is required for prolonged biological activity (PubMed:26902720)
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SwissProt ID
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Synonyms
Protein Wnt-8a antibody; WNT 8A antibody; Wnt 8d antibody
Documentation
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