1. Apoptosis
  2. Apoptosis
  3. Anticancer agent 104

Anticancer agent 104 has anticancer activity, and induces cancer cell apoptosis.

For research use only. We do not sell to patients.

Anticancer agent 104 Chemical Structure

Anticancer agent 104 Chemical Structure

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Description

Anticancer agent 104 has anticancer activity, and induces cancer cell apoptosis[1].

In Vitro

Anticancer agent 104 (Compound 4l) (48 h) is toxic to HepG2 cells (IC50: 31.39 μM)[1].
Anticancer agent 104 (10-200 μg/mL, 48 h) exhibits volume reduction, chromatin margination, and eventually formed apoptotic vesicles[1].
Anticancer agent 104 (10-100 μg/mL, 48 h) induces HepG2 cell apoptosis[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis[1]

Cell Line: Calu-1, SK-BR-3, HUH-7, 786-O, SK-OV-3 cells
Concentration: 0-200 μM approximately
Incubation Time: 48 h
Result: Shows cytotoxic activities with IC50s of 78.34, 44.18, 75.18, 91.67, 112.19 μM.

Apoptosis Analysis[1]

Cell Line: HepG2 cells
Concentration: 10, 50 and 100 μg/mL
Incubation Time: 48 h
Result: Showed apoptotic rate of 23.67%, 41.21% and 61.16% respectively.
Molecular Weight

636.87

Formula

C34H47F3N2O2S2

SMILES

[H][C@@]12CCCN3CCC[C@@]([C@@]31[H])([C@@](CCCC(OC4CC5CCC4(C5(C)C)C)=O)(N(C2)C(SCC6=CC=C(C=C6)C(F)(F)F)=S)[H])[H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Anticancer agent 104 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Anticancer agent 104
Cat. No.:
HY-149231
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