Cerastecin D
Cerastecin D (compound 1) is an antibacterial agent. Cerastecin D shows inhibition on Acinetobacter baumannii ATCC19606 with MITC95 values of 165 nM.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 3018085-89-4
- Formel: C36H29F2N7O9S2
- Molecular Weight:805.78
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MT4 | EC50 |
>42 μM
Compound: 1
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Cytotoxicity against GFP fused human MT4 cells cultured under serum free condition for 24 hrs by CellTiter-Glo assay
Cytotoxicity against GFP fused human MT4 cells cultured under serum free condition for 24 hrs by CellTiter-Glo assay
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[PMID: 39172133] |
Chemical Information
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CAS. Nr. 3018085-89-4
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Molecular Weight 805.78
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Formel C36H29F2N7O9S2
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SMILES
O=C(O)C1=CC(OC2CN(CC3=CC=C(NS(=O)(C4=CN(C5=CC=C(F)C=C5)N=C4)=O)C(C(O)=O)=C3)C2)=CC=C1NS(=O)(C6=CN(C7=CC=C(F)C=C7)N=C6)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
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Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Cerastecin D Related Classifications
HY-162839 Related Classifications
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