ATG5/TECAIR-IN-2
ATG5/TECAIR-IN-2 is an ATG5 inhibitor with target IC50 values >33 μM.ATG5/TECAIR-IN-2 disrupts protein-protein interactions between ATG5 and ATG16L1, and between ATG5 and TECAIR.ATG5/TECAIR-IN-2 inhibits autophagy in mammalian cells.
For research use only. We do not sell to patients.
- CAS No.: 2841473-95-6
- Formula: C30H22N2O5
- Molecular Weight:490.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
ATG5/TECAIR-IN-2 (compound 17f) does not exhibit obvious inhibitory activity against the ATG5-ATG16L1 protein-protein interaction, and shows no meaningful inhibitory activity against the ATG5-TECAIR protein-protein interaction with an IC50 greater than 33 μM[1].
ATG5/TECAIR-IN-2 (20 μM; 6 h) inhibits autophagy in COS-7 cells, resulting in an autophagy incidence of 8.30%[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:COS-7 cells
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Concentration:20 μM
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Incubation Time:6 h
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Result:Reduced autophagy incidence to 8.30%.
Chemical Information
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CAS No. 2841473-95-6
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Molecular Weight 490.51
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Formula C30H22N2O5
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SMILES
NC(C1=CC=CC(C2=CC=C(O2)/C=C(C3=O)\C=C(C4=CC=CC=C4)N3CC5=CC=C(C=C5)C(O)=O)=C1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ATG5/TECAIR-IN-2 Related Classifications
HY-183828 Related Classifications
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