1. PROTAC Apoptosis
  2. Ligands for Target Protein for PROTAC Bcl-2 Family
  3. BCL-xL ligand 4

BCL-xL ligand 4 is a BCL-xL ligand that can be used for the synthesis of PROTACs, such as PZ703b (HY-115718), PZ703b TFA (HY-115718A), and PZ703b hydrochloride (HY-115718B).

For research use only. We do not sell to patients.

BCL-xL ligand 4

BCL-xL ligand 4 Chemical Structure

CAS No. : 3027548-08-6

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Description

BCL-xL ligand 4 is a BCL-xL ligand that can be used for the synthesis of PROTACs, such as PZ703b (HY-115718), PZ703b TFA (HY-115718A), and PZ703b hydrochloride (HY-115718B)[1][2].

IC50 & Target[1]

Bcl-xL

 

Molecular Weight

989.63

Formula

C47H56ClF3N6O6S3

CAS No.
SMILES

ClC1=CC=C(C=C1)C2=C(C[C@](CN)(CC2)C)CN3CCN(CC3)C4=CC=C(C=C4)C(NS(C5=CC(S(=O)(C(F)(F)F)=O)=C(C=C5)N[C@H](CCN6CCOCC6)CSC7=CC=CC=C7)(=O)=O)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
BCL-xL ligand 4
Cat. No.:
HY-184547
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