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United States

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Cat. No.: HY-176132

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BI 1181181 MZ

BI 1181181 MZ is a potent and selective BACE1 inhibitor. BI 1181181 MZ can be used in the research for Alzheimer’s disease.

For research use only. We do not sell to patients.

Formula: C₃₁H₃₇FN₄O₅
Molecular Weight:564.65

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

BI 1181181 MZ Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

BI 1181181 MZ is a potent and selective BACE1 inhibitor. BI 1181181 MZ can be used in the research for Alzheimer’s disease^[1].

All Beta-secretase Isoforms :

BACE1
BACE2

Chemical Information

Molecular Weight 564.65
Formula C₃₁H₃₇FN₄O₅
SMILES

N#CC1=CC=C(C[C@]2(C[C@H](C)[C@@H](O)[C@H](C)C2)[C@]34C(N(CC(F)(C)C)C(N)=N4)=O)C3=C1.OC([C@H](C5=CC=CC=C5)O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Guisheng Li, Process Development of the BACE Inhibitors BI 1147560 BS and BI 1181181 MZ. Organic Process Research & Development. Vol 26/Issue 12.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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BI 1181181 MZ

All Beta-secretase Isoforms