Boc-NH-C12-NH2
Based on 1 Customer Validation
Boc-NH-C12-NH2 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 99.99%
- CAS No.: 109792-60-1
- Formula: C17H36N2O2
- Molecular Weight:300.48
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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Alkyl/ether |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 109792-60-1
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Appearance Solid
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Molecular Weight 300.48
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Formula C17H36N2O2
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Color Off-white to light yellow
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SMILES
NCCCCCCCCCCCCNC(OC(C)(C)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 35 mg/mL (116.48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (265 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3280 mL | 16.6400 mL | 33.2801 mL | 83.2002 mL |
| 5 mM | 0.6656 mL | 3.3280 mL | 6.6560 mL | 16.6400 mL | |
| 10 mM | 0.3328 mL | 1.6640 mL | 3.3280 mL | 8.3200 mL | |
| 15 mM | 0.2219 mL | 1.1093 mL | 2.2187 mL | 5.5467 mL | |
| 20 mM | 0.1664 mL | 0.8320 mL | 1.6640 mL | 4.1600 mL | |
| 25 mM | 0.1331 mL | 0.6656 mL | 1.3312 mL | 3.3280 mL | |
| 30 mM | 0.1109 mL | 0.5547 mL | 1.1093 mL | 2.7733 mL | |
| 40 mM | 0.0832 mL | 0.4160 mL | 0.8320 mL | 2.0800 mL | |
| 50 mM | 0.0666 mL | 0.3328 mL | 0.6656 mL | 1.6640 mL | |
| 60 mM | 0.0555 mL | 0.2773 mL | 0.5547 mL | 1.3867 mL | |
| 80 mM | 0.0416 mL | 0.2080 mL | 0.4160 mL | 1.0400 mL | |
| 100 mM | 0.0333 mL | 0.1664 mL | 0.3328 mL | 0.8320 mL |
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