C18-PEG2000-COOH
C18-PEG2000-COOH is a conjugate composed of an octadecyl group (C18 aliphatic chain), a PEG chain, and a carboxyl group (-COOH). C18-PEG2000-COOH combines the membrane compatibility of lipids with the carboxyl group, which can form amide bonds with primary amines via EDC/NHS activation, making it suitable for research in biomaterial construction and drug delivery.
For research use only. We do not sell to patients.
- Molecular Weight:2000 (Average)
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vitro
The structure of C18-PEG-COOH comprises three key parts, each acting synergistically:
C18: The long-chain alkyl group imparts significant hydrophobicity to the molecule, enabling self-assembly and allowing it to form micelles, vesicles, or embed in lipid bilayers in aqueous environments.
PEG chain: Serving as a hydrophilic spacer, it forms a hydration layer on the particle surface, reducing non-specific adsorption and immune system clearance, thus prolonging the carrier's circulation time in vivo.
Carboxyl group (-COOH): Located at the end of the PEG chain, it acts as a reaction interface, capable of condensation or esterification reactions with amino groups, hydroxyl groups, etc.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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Molecular Weight 2000 (Average)
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SMILES
O=C(NCCOCC(O)=O)CCCCCCCCCCCCCCCCC.[n]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)