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Cat. No.: HY-W355652

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Fluvoxamine acid

Fluvoxamino acid is the major metabolite of Fluvoxamine (HY-B0103) produced in the human body, and acts as a 5-HT reuptake transporter inhibitor. Fluvoxamino acid exhibits weaker inhibitory activity against 5-HT reuptake than its parent compound Fluvoxamine, and can synergistically regulate 5-HT transmission with the parent compound. Fluvoxamino acid can be used in the research of major depressive disorder.

For research use only. We do not sell to patients.

CAS No.: 88699-91-6
Formula: C₁₄H₁₇F₃N₂O₃
Molecular Weight:318.29

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Fluvoxamine acid Chemical Structure

CAS No.: 88699-91-6

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Biological Activity
- Description
- IC₅₀ & Target
- In Vivo
Chemical Information
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Biological Activity

Description

IC₅₀ & Target^[1]

5-HT Receptor

All 5-HT Receptor Isoforms :

In Vivo

Fluvoxamino acid (FLA) is positively correlated with the improvement of depressive symptoms, and its concentration in responders is significantly higher^[1].
Fluvoxamino acid exhibits weaker 5-HT reuptake inhibitory activity than its parent drug, but has higher polarity. It is hypothesized that FLA has a lower plasma protein binding rate and a higher free concentration in the central nervous system, thereby exerting antidepressant effects^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 88699-91-6
Molecular Weight 318.29
Formula C₁₄H₁₇F₃N₂O₃
SMILES

C(C/C(=N\OCCN)/C1=CC=C(C=C1)C(F)(F)F)CC(=O)O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Gerstenberg G, et al. Relationship between clinical effects of fluvoxamine and the steady-state plasma concentrations of fluvoxamine and its major metabolite fluvoxamino acid in Japanese depressed patients. Psychopharmacology. 2003 Jun;167(4):443-8. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vivo
Chemical Information
Purity & Documentation
References

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Fluvoxamine acid

All 5-HT Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Fluvoxamine acid Related Classifications

HY-W355652 Related Classifications