1,12-Dibromododecane
Based on 1 Customer Validation
1,12-Dibromododecane is a PROTAC linker that can be used in the synthesis of PROTACs.
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- Pureté : 98.95%
- CAS No.: 3344-70-5
- Formule: C12H24Br2
- Masse moléculaire:328.13
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Stockage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
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Help & FAQs
Voir tous les produits spécifiques à Isoform PROTAC Linkers
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Activité biologique
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E63 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3344-70-5
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Appearance Solid
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Masse moléculaire 328.13
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Formule C12H24Br2
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Color White to off-white
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SMILES
BrCCCCCCCCCCCCBr
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvant et solubilité
In Vitro:
DMSO : 100 mg/mL (304.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (237 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0476 mL | 15.2379 mL | 30.4757 mL | 76.1893 mL |
| 5 mM | 0.6095 mL | 3.0476 mL | 6.0951 mL | 15.2379 mL | |
| 10 mM | 0.3048 mL | 1.5238 mL | 3.0476 mL | 7.6189 mL | |
| 15 mM | 0.2032 mL | 1.0159 mL | 2.0317 mL | 5.0793 mL | |
| 20 mM | 0.1524 mL | 0.7619 mL | 1.5238 mL | 3.8095 mL | |
| 25 mM | 0.1219 mL | 0.6095 mL | 1.2190 mL | 3.0476 mL | |
| 30 mM | 0.1016 mL | 0.5079 mL | 1.0159 mL | 2.5396 mL | |
| 40 mM | 0.0762 mL | 0.3809 mL | 0.7619 mL | 1.9047 mL | |
| 50 mM | 0.0610 mL | 0.3048 mL | 0.6095 mL | 1.5238 mL | |
| 60 mM | 0.0508 mL | 0.2540 mL | 0.5079 mL | 1.2698 mL | |
| 80 mM | 0.0381 mL | 0.1905 mL | 0.3809 mL | 0.9524 mL | |
| 100 mM | 0.0305 mL | 0.1524 mL | 0.3048 mL | 0.7619 mL |
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