BMS-181885
BMS-181885 is a selective 5-HT1 receptor agonist and a ligand for 5-HT1B/1D receptors. BMS-181885 exhibits anti-migraine activity. BMS-181885 can be used in the research of neurological diseases such as migraine.
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- CAS No.: 165250-47-5
- Formule: C25H28N6O3
- Masse moléculaire:460.53
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
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5-HT1 Receptor |
Chemical Information
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CAS No. 165250-47-5
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Masse moléculaire 460.53
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Formule C25H28N6O3
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SMILES
O=C1C(C(NC2=CC3=C(NC=C3CCCN4CCN(C5=NC=NC=C5OC)CC4)C=C2)=C1C)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Srinivas NR, et al. Absolute bioavailability and dose proportionality of BMS-181885, an antimigraine agent, following the administration of single intranasal doses to cynomolgus monkeys. J Pharm Sci. 1998 Sep;87(9):1170-2. [Content Brief]
[3]. Saxena PR, et al. BMS-181885, a 5-HT1B/1D receptor ligand, in experimental models predictive of antimigraine activity and coronary side-effect potential. Eur J Pharmacol. 1998 Jun 26;351(3):329-39. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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