country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-187236

Copy Link Print Information

DOPE-PEG1000-CTP

Name: DOPE-PEG1000-CTP
Brand: MedChemExpress
SKU: HY-187236
Availability: PreOrder

(Synonyms: DOPE-PEG1000-APWHLSSQYSRT)

DOPE-PEG1000-CTP is a functionalized PEGylated lipid conjugate composed of three modular components: dioleoylphosphatidylethanolamine (DOPE) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 1000 Da, and CTP (cardiotropic targeting peptide) (HY-P4094) as the terminal targeting/functional ligand. DOPE-PEG1000-CTP can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers, conferring cardiac targeting capability.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

DOPE-PEG1000-CTP Chemical Structure

Size

Prix

Stock

Quantité

Amount: USD 0.00

* Veuillez sélectionner la quantité avant d'ajouter des articles.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

In Vitro

DOPE-PEG1000-CTP is specifically designed for active targeting nanomedicine applications. It can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against brain endothelial cell receptors/CNS-specific transport mechanisms.
Composition and role of each component:
1. PEG1000 (polyethylene glycol, MW 1000): Hydrophilic polymer spacer arm that forms a steric corona around nanoparticles, reducing opsonization and reticuloendothelial system (RES) clearance, prolonging circulation half-life, and providing spatial separation between the lipid surface and targeting ligand.
2. CTP: Targeting ligand-can be reversibly linked (e.g., via enolase, thiol groups) to a carrier (e.g., miRNA), thereby enabling specific delivery to cardiomyocytes rather than all other organs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

SMILES

[DOPE-PEG1000-CTP]
Synonyms

DOPE-PEG1000-APWHLSSQYSRT
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.