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Cat. No.: HY-170896

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iso-A11B5C1

Iso-A11B5C1 is an ionizable lipid that can be used in the synthesis of lipid nanoparticles (LNP). Iso-A11B5C1 is particularly suitable for muscle-specific mRNA delivery.

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CAS No.: 3063868-70-9
Formule: C₄₁H₇₉N₃O₃
Masse moléculaire:662.08

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

iso-A11B5C1 Chemical Structure

CAS No.: 3063868-70-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
- In Vivo
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

Iso-A11B5C1 is an ionizable lipid that can be used in the synthesis of lipid nanoparticles (LNP). Iso-A11B5C1 is particularly suitable for muscle-specific mRNA delivery^[1].

In Vitro

iso-A11B5C1 LNP exhibits significant luciferase expression levels in HeLa cells after encapsulating Firefly Luciferase mRNA (HY-174790)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

iso-A11B5C1 LNP (i.m.) exhibits high mRNA expression in the muscle region and induces a strong humoral and cellular immune response in mice, suggesting its potential as an mRNA vaccine vector^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3063868-70-9
Masse moléculaire 662.08
Formule C₄₁H₇₉N₃O₃
SMILES

CCCCCC(C)CCC(OCCCCCC(NCCN1CCCC1)C(NCCCCCCCC/C=C\CCCCCCCC)=O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Bowen Li, et al. Systems and methods for ai-based ionizable lipid development for lipid nanoparticle (lnp)-based cargo molecule delivery. WO2024234088.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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100 mg

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