MetAP-2 modulator-1
MetAP-2 modulator-1 is a MetAP-2 modulator. MetAP-2 modulator-1 reduces the MetAP-2 enzyme level in cells. MetAP-2 modulator-1 exhibits anticancer effects against neuroblastoma. MetAP-2 modulator-1 can be used in studies related to neuroblastoma.
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- Formule: C20H15FN4O2S
- Masse moléculaire:394.42
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
In Vitro
MetAP-2 modulator-1 (Compound 4e) (2.5 μg/mL; 24 h) significantly reduces MetAP-2 enzyme levels in human neuroblastoma SH-SY5Y cells, resulting in a measured level of 8.8 ng/μg protein after 24 h exposure at 2.5 μg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:human neuroblastoma SH-SY5Y cells
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Concentration:2.5 μg/mL
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Incubation Time:24 h
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Result:Reduced MetAP-2 level to 8.8 ng/μg protein, which was a significant decrease compared to unexposed control cells (56.4 ng/μg protein) and positive control fumagillin (85.9 ng/μg protein).
Chemical Information
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Masse moléculaire 394.42
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Formule C20H15FN4O2S
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SMILES
OC1=CC=C(C=C1)/C=N/NC(CC2=CSC3=NC(C4=CC=C(C=C4)F)=CN23)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MetAP-2 modulator-1 Related Classifications
HY-184384 Related Classifications
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