PROTAC CDK6 Degrader 2
PROTAC CDK6 Degrader 2 (compound 48b), the active form of PROTAC CDK6 Degrader 1 (HY-180277), is a potent and selective PROTAC CDK6 degrader that binds strongly to KLHDC2 (KD = 0.005 μM). PROTAC CDK6 Degrader 2 functions through a KLHDC2-dependent and ubiquitin-proteasome-mediated mechanism. PROTAC CDK6 Degrader 2 can be used for cancer research.
(Pink: CDK6 ligand (HY-180278); Blue: KLHDC2 ligand (HY-180263); Black: linker).
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Formule: C69H87N15O8
- Masse moléculaire:1254.52
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Activité biologique
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CDK6 |
Chemical Information
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Masse moléculaire 1254.52
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Formule C69H87N15O8
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SMILES
O=C([C@@H]1CN(CCC1)C2=C3C=CC=CC3=CN=C2)N(CC4=CN(N=C4)CC(O)=O)CCNC([C@H]5CC[C@H](C(N6CCC7(CC(C7)N8CCC(CC8)C(N9CCN(C%10=CN=C(NC%11=NC=C%12C(N(C(C(C(C)=O)=C%12C)=O)C%13CCCC%13)=N%11)C=C%10)CC9)=O)CC6)=O)CC5)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PROTAC CDK6 Degrader 2 Related Classifications
HY-180262 Related Classifications
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