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Cat. No.: HY-173445

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RIPK1-IN-30

RIPK1-IN-30 (compound 24) is a potent RIPK1 inhibitor with an IC₅₀ of 2.01 μM. RIPK1-IN-30 exhibits protective effects in HT-29 cell model of TSZ-induced necroptosis with an EC₅₀ of 6.77 μM.

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Formule: C₂₇H₂₅FN₂O₄
Masse moléculaire:460.50

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

RIPK1-IN-30 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Voir tous les produits spécifiques à Isoform RIP kinase :

Chemical Information

Masse moléculaire 460.50
Formule C₂₇H₂₅FN₂O₄
SMILES

FC1=CC=CC(CN2C(N(C3=CC=CC(C(CC4=CC(OCCO5)=C5C=C4)=O)=C3)CCC2)=O)=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Liu B, et al. Discovery and Characterization of Novel Receptor-Interacting Protein Kinase 1 Inhibitors Using Deep Learning and Virtual Screening. ACS Chem Neurosci. 2025 Apr 16;16(8):1617-1630. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Activité biologique
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Chemical Information
Pureté et documentation
Références

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RIPK1-IN-30

Voir tous les produits spécifiques à Isoform RIP kinase

Activité biologique

Description

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

RIPK1-IN-30 Related Classifications

HY-173445 Related Classifications

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Keywords

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