8 Results for "

diarylheptanoid inhibitor

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "diarylheptanoid inhibitor" in MCE Product Catalog:

Cat. No.: HY-N3225
CAS No.: 33606-81-4
Myricanol is a diarylheptanoid and a Nampt activator. Myricanol exerts anti-inflammatory effects and alleviates glucocorticoid-induced muscle atrophy by increasing Sirtuin 1 (SIRT1) and PRDX5 activities while regulating inflammatory factors. Myricanol exhibits growth inhibition and induces apoptosis in human lung adenocarcinoma A549 cells. Myricanol promotes autophagy-mediated clearance of microtubule-associated protein tau to exert neuroprotective effects. Myricanol protects cardiovascular function by inhibiting PDGFRβ and NF-κB signaling pathways. Myricanol activates mitochondrial transcription factor A (TFAM) expression to exert anti-renal fibrosis effects. Myricanol improves insulin resistance through AMPK activation .
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Cat. No.: HY-N16524
CAS No.: 2151847-03-7
Alpinin A is a diarylheptanoid found in the rhizomes of Alpinia officinarum. Alpinin A can strongly inhibit the aggregation of α-synuclein with inhibition rate of 66% at 10 μM. Alpinin A can be used for the research of neurological disease, such as Parkinson’s disease .
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Cat. No.: HY-N4044
CAS No.: 41137-86-4
Synonyms: (5S)-Hirsutanonol
Hirsutanonol ((5S)-Hirsutanonol) is a diarylheptanoid that can be isolated from the bark of Alnus hirsute var. sibirica. Hirsutanonol inhibits cyclooxygenase-2 (COX-2) expression. Hirsutanonol has anti-filarial with an IC50 value of 44.11 μg/mL for microfilariae .
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Cat. No.: HY-N15613
CAS No.: 408324-13-0
α-Synuclein inhibitor 14 (Compound 3) is a diarylheptanoid that can be isolated from Alpinia officinarum. α-Synuclein inhibitor 14 can inhibit the aggregation of α-synuclein, with an inhibition rate of 72.4% at a concentration of 10 μM. α-Synuclein inhibitor 14 can be used in the research of neurodegenerative diseases such as Parkinson's disease .
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Cat. No.: HY-N15215
CAS No.: 1004319-60-1
Antiviral agent 64 (Compound 12) is a diarylheptanoid that can be isolated from Alpinia officinarum. Antiviral agent 64 exhibits cytotoxicity in human neuroblastoma cell IMR-32 with an IC50 of 0.23 μM. Antiviral agent 64 exhibits antiviral efficacy, that inhibits RSV, poliovirus, measles virus, HSV-1, and influenza virus H1N1, with EC50 of 13.3, 3.7, 6.3, 5.7, and <10 μg/mL, respectively .
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Cat. No.: HY-N17436
CAS No.: 138870-92-5
Demethoxyhexahydrocurcumin is a Curcumin (HY-N0005) biotransformation metabolite and diarylheptanoid with antioxidant and antimicrobial activities. Demethoxyhexahydrocurcumin scavenges free radicals, inhibits cancer cell viability, and suppresses microbial growth. Demethoxyhexahydrocurcumin can be used for the research of colorectal cancer .
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Cat. No.: HY-180408
CAS No.: 90803-80-8
Target:  

Influenza Virus

Domaines de recherche:  

Infection

Platyphylloside is an anti-virus agent that can be isolated from the bark of Alnus japonica. Platyphylloside exhibits activity against H9N2 avian influenza virus. Platyphylloside can be used for the research of influenza .
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Cat. No.: HY-N3043A
CAS No.: 56973-65-0
(E/Z)-Platyphyllenone is a diarylheptanoid compound that can be found in Alnus viridis ssp. viridis. (E/Z)-Platyphyllenone inhibits the biosynthesis of violacein, but stimulates the production of AHL and AHQ quorum-sensing signal molecules as well as the synthesis of pyocyanin in Pseudomonas aeruginosa PAO1, and exhibits strong cytotoxicity against human lung fibroblasts. (E/Z)-Platyphyllenone can be used in studies on Pseudomonas aeruginosa .
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