Carbazochrome (sodium sulfonate trihydrate)
Carbazochrome sodium sulfonate trihydrate (AC-17 trihydrate) is a capillary stabilizer with anti-hemorrhagic properties and can be used in hemostasis-related research.
For research use only. We do not sell to patients.
- CAS No.: 2666934-58-1
- Formula: C10H17N4NaO8S
- Molecular Weight:376.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
In Vitro
Carbazochrome (0.1-10 μM) sodium sulfonate trihydrate inhibits the Bradykinin induced and thrombin-induced formation of [3H]IP3 in a concentration-dependent manner[1]. Carbazochrome (0.1-1 μM) sodium sulfonate trihydrate, when included from 30 min before stimulation, significantly suppressed the enhancement of permeability induced by vasoactive substances[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2666934-58-1
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Molecular Weight 376.32
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Formula C10H17N4NaO8S
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SMILES
O=C(N/N=C1C=C2C(N(C(S(=O)(O[Na])=O)C2)C)=CC/1=O)N.O.O.O
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Synonyms
AC-17 trihydrate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Toshiaki Sendo, et al. Carbazochrome sodium sulfonate (AC-17) reverses endothelial barrier dysfunction through inhibition of phosphatidylinositol hydrolysis in cultured porcine endothelial cells. Naunyn Schmiedebergs Arch Pharmacol. 2003 Sep;368(3):175-80. [Content Brief]
[2]. Toshiaki Sendo, et al. Carbazochrome attenuates pulmonary dysfunction induced by a radiographic contrast medium in rats. Eur J Pharmacol. 2002 Aug 23;450(2):203-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Carbazochrome (sodium sulfonate trihydrate) Related Classifications
HY-W1059167 Related Classifications
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