1282512-48-4
1282512-48-4
Chemical Structure
Taselisib
Synonym(s): GDC-0032; RG-7604
- CAS No.: 1282512-48-4
- Formula:C24H28N8O2
- Molecular Weight:460.53
IUPAC Name: 2-(4-(2-(1-isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)-1H-pyrazol-1-yl)-2-methylpropanamide
InChIKey: BEUQXVWXFDOSAQ-UHFFFAOYSA-N
SMILES: CC(C)N1C(C2=CN3C(C(C(OCC3)=C4)=CC=C4C5=CN(C(C)(C(N)=O)C)N=C5)=N2)=NC(C)=N1
Biological Activity: Taselisib (GDC-0032) is a potent PI3K inhibitor targets PIK3CA mutations, with Kis of 0.12 nM, 0.29 nM, 0.97 nM, and 9.1 nM for PI3Kδ, PI3Kα, PI3Kγ and PI3Kβ, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Taselisib | 99.75% | Taselisib (GDC-0032) is a potent PI3K inhibitor targets PIK3CA mutations, with Kis of 0.12 nM, 0.29 nM, 0.97 nM, and 9.1 nM for PI3Kδ, PI3Kα, PI3Kγ and PI3Kβ, respectively. | ||||||||||||||||||||
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Keywords
