1334673-53-8

JAK-IN-1 Chemical Structure
1334673-53-8

Chemical Structure

JAK-IN-1

  • CAS No.: 1334673-53-8
  • Formula:C20H24N6O2
  • Molecular Weight:380.44

IUPAC Name: (R)-N-(1-(3-cyanoazetidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)-2-cyclopropyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide

InChIKey: SIEMFXMJGAMFQR-INIZCTEOSA-N

SMILES: O=C(C1=CNC2=NC=C(C3CC3)N=C21)N[C@@H](C(N4CC(C#N)C4)=O)C(C)(C)C

Biological Activity: JAK-IN-1 is a JAK1/2/3 inhibitor with IC50s of 0.26, 0.8 and 3.2 nM, respectively. JAK-IN-1 shows improved selectivity for JAK3 over JAK1.

Cat. No. Product Name Purity Description Pricing
HY-13827 		JAK-IN-1 98.39% JAK-IN-1 is a JAK1/2/3 inhibitor with IC50s of 0.26, 0.8 and 3.2 nM, respectively. JAK-IN-1 shows improved selectivity for JAK3 over JAK1.
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