1334673-53-8
1334673-53-8
Chemical Structure
JAK-IN-1
- CAS No.: 1334673-53-8
- Formula:C20H24N6O2
- Molecular Weight:380.44
IUPAC Name: (R)-N-(1-(3-cyanoazetidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)-2-cyclopropyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide
InChIKey: SIEMFXMJGAMFQR-INIZCTEOSA-N
SMILES: O=C(C1=CNC2=NC=C(C3CC3)N=C21)N[C@@H](C(N4CC(C#N)C4)=O)C(C)(C)C
Biological Activity: JAK-IN-1 is a JAK1/2/3 inhibitor with IC50s of 0.26, 0.8 and 3.2 nM, respectively. JAK-IN-1 shows improved selectivity for JAK3 over JAK1.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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JAK-IN-1 | 98.39% | JAK-IN-1 is a JAK1/2/3 inhibitor with IC50s of 0.26, 0.8 and 3.2 nM, respectively. JAK-IN-1 shows improved selectivity for JAK3 over JAK1. | ||||||||||||||||||||
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