1346601-02-2
1346601-02-2
Chemical Structure
Itopride-d6 hydrochloride
Synonym(s): HSR803-d6 hydrochloride
- CAS No.: 1346601-02-2
- Formula:C20H21D6ClN2O4
- Molecular Weight:400.93
IUPAC Name: N-(4-(2-(bis(methyl-d3)amino)ethoxy)benzyl)-3,4-dimethoxybenzamide hydrochloride
InChIKey: ZTOUXLLIPWWHSR-TXHXQZCNSA-N
SMILES: [2H]C([2H])([2H])N(C([2H])([2H])[2H])CCOC(C=C1)=CC=C1CNC(C2=CC(OC)=C(C=C2)OC)=O.Cl
Biological Activity: Itopride-d6 (hydrochloride) is deuterium labeled Itopride (hydrochloride). Itopride hydrochloride (HSR803), a gastroprokinetic Benzamide (HY-Z0283) derivative, is an inhibitor of acetylcholinesterase (AChE) and dopamine D2 receptor[1][2].
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Itopride-d6 hydrochloride | Itopride-d6 (hydrochloride) is deuterium labeled Itopride (hydrochloride). Itopride hydrochloride (HSR803), a gastroprokinetic Benzamide (HY-Z0283) derivative, is an inhibitor of acetylcholinesterase (AChE) and dopamine D2 receptor. | |||||||||||||||||||||
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Itopride hydrochloride (Standard) | ≥98% | Itopride (hydrochloride) (Standard) is the analytical standard of Itopride (hydrochloride). This product is intended for research and analytical applications. Itopride (HSR803) hydrochloride is a potent dopamine-2 antagonist and an acetylcholine esterase (AChE) inhibitor. Itopride hydrochloride enhances gastric motility through both antidopaminergic and anti-acetylcholinesterasic actions, can be used as a gastrointestinal prokinetic agent. Itopride can be used for researching gastro-esophageal reflux disease (GERD). | ||||||||||||||||||||
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Itopride hydrochloride | 99.84% | Itopride (HSR803) hydrochloride is a potent dopamine-2 antagonist and an acetylcholine esterase (AChE) inhibitor. Itopride hydrochloride enhances gastric motility through both antidopaminergic and anti-acetylcholinesterasic actions, can be used as a gastrointestinal prokinetic agent. Itopride can be used for researching gastro-esophageal reflux disease (GERD). | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Hyun Chul Lim, et al. Effect of Itopride Hydrochloride on the Ileal and Colonic Motility in Guinea Pig In Vitro. Effect of Itopride Hydrochloride on the Ileal and Colonic Motility in Guinea Pig In Vitro. Yonsei Med J. 2008 Jun 30;49(3):472-8. [Content Brief]
